Education
PhD in Biochemistry - University of Alberta, Canada, 2018
Publications
- Xiao T, Sun L, Zhang M, Li Z, Haura EB, Schönbrunn E, Ji H (2021). Synthesis and structural characterization of a monocarboxylic inhibitor for GRB2 SH2 domain. Bioorg Med Chem Lett 51:128354 PMID 34506932
- Hanna CB, Mudaliar D, John K, Allen CL, Sun L, Hawkinson JE, Schönbrunn E, Georg GI, Jensen JT (2020). Development of WEE2 kinase inhibitors as novel non-hormonal female contraceptives that target meiosis. Biol Reprod. 103:368-377 PMID 32667031
- Sun, L., Huang, Y., Edward, R. Glover, J.N.M. Structural insight into BLM recognition by TopBP1. Structure 25，1582-1588. (2017)
- Ayoub, A., Ahmed, R., Tilli, T., Arakawa, K., Sun, L., Glover, J.N.M., Klobukowski, M., Tuszynski, J. Antitumor activity of lankacidin antibiotics is due to microtubule stabilization via a taxol-like mechanism. Journal of Medicinal Chemistry. 59(20): 9532-9540. (2016)
- White, E., Sun, L., Ma Z., Beckta, J., Danzig, B., Hacker, D., Huie, Melissa., William, D., Edwards, R., Valerie, K., Glover, J.N.M., Hartman, M. A peptide library approach to uncover phosphomimetic inhibitors of BRCA1 C-terminal domain. ACS Chemical Biology, 10(5): 1198-208. (2015)
- Leung, C., Sun, L., Gong, Z., Burkat, M., Edwards, R., Assmus, M., Chen, J., Glover, J.N.M. Structural insights into recognition of MDC1 by TopBP1 in DNA replication checkpoint control. Structure. 21,1450-1459. (2013)
- Song, X., Lopez-Campistrous, A., Sun, L., Dower, N.A., Kedei, N., Yang, J., Kelsey, J.S., Lewin, N.E., Esch, T.E., Blumberg, P.M., Stone, J.C. RasGRPs are targets of the anti-cancer agent ingenol-3-angelate. PLoS One.8(8), e72331. (2013)
E. Schönbrunn Laboratory
