Karen M Mann, PhD
Principal Investigator
Dr. Karen Mann earned her PhD in Genetics from Case Western Reserve University, where she developed her expertise in modeling human disease in mice. She did her post-doctoral training in Singapore with Neal Copeland and Nancy Jenkins, using Sleeping Beauty (SB) Insertional mutagenesis for cancer gene discovery in mouse models of several human cancers. Dr. Mann developed an SB model of pancreatic cancer and uncovered novel interacting genes that promote disease progression and impact patient survival. Her lab employs the SB model of pancreatic cancer to uncover novel regulatory pathways that can be harnessed to treat metastatic disease. Her lab also uses SB to study clonal evolution in mouse models of pancreatic cancer and myeloid leukemia and its impact on metastatic potential and drug resistance. Dr. Mann is dedicated to training young scientists at all levels.
Lab Alumni
Justin Newberg, PhD, Foundation Medicine, Cambridge MA
Suman Govindaraju, PhD, Scientific Scientific Manager, CRO, India
Tiffany Arnold, MS, Sr. Associate Scientist, Forge Biologics, Columbus, OH
Michelle Maurin, MS, Advanced Research Scientist at USF, Tampa FL
Montana Young, Pre-doctoral Candidate, Vanderbilt University
Cierra Kenney, BS