Karen Mann, PhD, Principle Investigator

Dr. Mann earned her PhD in Genetics from Case Western Reserve University, where she developed her expertise in modeling human disease in mice. She did her post-doctoral training in Singapore with Neal Copeland and Nancy Jenkins, using Sleeping Beauty Insertional mutagenesis for cancer gene discovery in mouse models of several human cancers. Dr. Mann developed a model of pancreatic cancer, for which few drivers were known, and uncovered novel interacting genes that impact patient outcome. She is passionate about contributing to the progress being made in understanding pancreatic cancer biology and has a particular interest in developing disease markers and treatments for metastatic disease. In addition, she has contributed to developing new sequencing approaches to study clonal evolution in Sleeping Beauty tumors and how this impacts metastatic potential and drug resistance. She is applying this approach to myeloid leukemia to uncover new drug targets that can be tested in preclinical models. Dr. Mann is dedicated to training young scientists at all levels.

Justin Newberg, PhD  

Research Analyst

Michelle Maurin, MS

Senior Research Associate

Tiffany Arnold, MS

Research Associate

Norma Pagan

Grants Administrator

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Post-doctoral Fellow

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Post-doctoral Fellow