Dr. Wei Mu and Ilke Tunali are annouced to give oral presentations at WMIC 2018. Dr. Mu will be giving two presentations; first on finding radiomics biomarkers in multimodality fused PET/CT images for the prediction of response to immunotherapies in NSCLC patients and second on radiomic biomarkers from fused PET/CT images for the prognosis of Cervical Cancer. Ilke Tunali will be presenting his work on clinical and radiomic predictors of rapid disease progression phenotypes among NSCLC patients that were treated with immunotherapies.
Drs. Smitha Pillai and Robert Gillies have received a Florida Biomedical Research Program grant focusing on "Targeting the lipogenic phenotype induced by extracellular acidosis in breast cancer"
Radiomics Workshop 2018
The annual Radiomics workshop sponsored by Moffitt will be held Oct. 15-16 at the Hyatt Regency Clearwater Beach, 301 S Gulfview Blvd, Clearwater, FL 33767. More information to be released soon.
Robert J. Gillies and his lab are focused on understanding cancers as complex, heterogeneous and dynamic systems. Along with his long-time collaborator, Robert A. Gatenby, they share a core belief that, due to genomic plasticity and microenvironmental heterogeneity, cancers can only be understood through the lens of Darwinian Evolution. Dr. Gillies is an experimentalist whose work spans molecular, cellular, animal models, and image analytics. He is the Martin Silberger Chair of Cancer Physiology, Director of the Center of Excellence in Cancer Imaging and Technology, and Scientific Director of the Small Animal Imaging Lab, SAIL.
May 2017, Cancer Research cover, from Arig Ibrahim-Hashim, Robert J. Gillies et al. "Defining Cancer Subpopulations by Adaptive Strategies Rather Than Molecular Properties Provides Novel Insights into Intratumoral Evolution"
Gillies Lab at the Moffitt PSOC Site Visit
Quantitative Imaging is an indispensable approach to study intratumoral heterogeneity. Dr. Gillies' group develops and applies Image Analytics to histological and radiological images to investigate the spatial relationships of cells and microenvironments in clinical and pro-clinical tumors.
Solid tumors are acidic due to elevated glycolysis combined with poor perfusion. Dr. Gillies has developed methods to image tumor pH, and study the causes and consequence of this acidity. Recent focus has been on developing methods to interfere with tumor acidosis for improving therapy in the clinic.