Selected Lab Publications:

• Histone deacetylase 11: A novel epigenetic regulator of myeloid derived suppressor cell expansion and function

• Selective HDAC6 inhibitors improve anti-PD-1 immune checkpoint blockade therapy by decreasing the anti-inflammatory phenotype of macrophages and down-regulation of immunosuppressive proteins in tumor cells

• Essential role for histone deacetylase 11 (HDAC11) in neutrophil biology

• Emerging role of BCR signaling inhibitors in immunomodulation of chronic lymphocytic leukemia

• Silencing of HDAC6 as a therapeutic target in chronic lymphocytic leukemia

• Epigenetic repolarization of T lymphocytes from chronic lymphocytic leukemia patients using 5-aza-2′-deoxycytidine

• A Molecular and Functional Analysis of Large Granular Lymphocyte Expansions in Chronic Myelogenous Leukemia Patients Treated With Tyrosine Kinase Inhibitors

• Restoring the Functional Immunogenicity of Chronic Lymphocytic Leukemia Using Epigenetic Modifiers

• The dual PI3Kδ/CK1ε inhibitor umbralisib exhibits unique immunomodulatory effects on CLL T cells

• HDAC6 inhibition alleviates T-cell dysfunction and enhances immune checkpoint blockade in chronic lymphocytic leukemia

• The role of Th17 cells in chronic lymphocytic leukemia: friend or foe?

• Optimization of In Vitro Th17 Polarization for Adoptive Cell Therapy in Chronic Lymphocytic Leukemia

• Mitigating T-cell mitochondrial dysfunction in CLL to augment CAR T-cell therapy: Evaluation in an immunocompetent model

• Impact of mitochondrial metabolism on T-cell dysfunction in chronic lymphocytic leukemia