
Authors:
Joshuah Otu¹; Cherell Cottrell‑Daniels, PhD, MPH²; Caseem Luck, MS¹; Brooke Bethune, BS¹; Brian Gonzalez, PhD¹; B. Lee Green, PhD¹
¹Moffitt Cancer Center, Department of Health Outcomes & Behavior
²Health Choice Network, Miami, FL
What This Study Is About
African American men face the highest rates of prostate cancer in the United States—experiencing both higher diagnosis rates and more than double the mortality risk compared to white men. While sleep problems and depression are known challenges for prostate cancer survivors, very little research has focused specifically on how these issues affect African American men.
This study explores how sleep, depression, and fatigue interact in older African American prostate cancer survivors.
Why This Matters
Understanding these relationships is important because:
- African American men experience unique stressors and health inequities
- Depression and poor sleep can significantly affect recovery and quality of life
- Fatigue may play a larger role in mental health than previously recognized
The goal is to identify where support and interventions are most needed.
How the Study Was Conducted
Researchers analyzed data from 149 African American prostate cancer survivors (age 65+) who completed the PROSPECT survey. Participants answered questions about:
- Sleep quality
- Depressive symptoms
- Fatigue
- Demographics and overall health
All measures were standardized using PROMIS scoring tools.
What We Found
Early findings show:
- Fatigue was the strongest predictor of depression in this group
- Sleep problems and depression were related, but only moderately
- When fatigue was taken into account, sleep alone did not fully explain depressive symptoms
This suggests that fatigue may be a key driver of mental health challenges among African American prostate cancer survivors.
What This Means for Survivors
These results highlight fatigue as a critical area for intervention. Addressing fatigue—through physical activity programs, symptom management, or supportive care—may help reduce depression and improve overall well‑being.
The study also reinforces the need for racially responsive, culturally informed care to ensure African American survivors receive equitable support.
Looking Ahead
Future research should:
- Include larger and more diverse samples
- Use objective sleep and activity measures
- Follow survivors over time to better understand changes in symptoms
This work contributes to closing gaps in survivorship care and improving quality of life for African American men living with prostate cancer.