Ruchi Ghildiyal, PhD

Postdoctoral Research Associate

Research Interests:

Long non coding RNAs, Prostate cancer, Tyrosine kinases


Selected Publications:

1. EGFR inhibitor BIBU induces apoptosis and defective autophagy in glioma cells. Ghildiyal R, Dixit D, Sen E (2012). Mol Carcinog. 2013 Dec;52(12):970-82. doi: 10.1002/mc.21938. Epub 2012 Jun 29.

  1. Concerted action of histone methyltransferases G9a and PRMT-1 regulates PGC-1α-RIG-I axis in IFNγ treated glioma cells. Ghildiyal R, Sen E. Cytokine. 2017 Jan;89:185-193. doi: 10.1016/j.cyto.2015.12.008. Epub 2015 Dec 22.
  1. CK2 induced RIG-I drives metabolic adaptations in IFNγ-treated glioma cells. Ghildiyal R, Sen E. Cytokine. 2017 Jan;89:219-228. doi: 10.1016/j.cyto.2015.10.009. Epub 2015 Nov 26.
  1. ATM-NFκB axis-driven TIGAR regulates sensitivity of glioma cells to radiomimetics in the presence of TNFα. Sinha S, Ghildiyal R, Mehta VS, Sen E. Cell Death Dis. 2013 May 2;4:e615. doi: 10.1038/cddis.2013.128.
  1. Guggulsterone sensitizes glioblastoma cells to Sonic hedgehog inhibitor SANT-1 induced apoptosis in a Ras/NFκB dependent manner. Dixit D, Ghildiyal R, Anto NP, Ghosh S, Sharma V, Sen E. Cancer Lett. 2013 Aug 19;336(2):347-58. doi: 10.1016/j.canlet.2013.03.025. Epub 2013 Mar 31.
  1. Chaetocin-induced ROS-mediated apoptosis involves ATM-YAP1 axis and JNK-dependent inhibition of glucose metabolism. Dixit D, Ghildiyal R, Anto NP, Sen E. Cell Death Dis. 2014 May 8;5:e1212. doi: 10.1038/cddis.2014.179
  1. CK2 inhibition induced PDK4-AMPK axis regulates metabolic adaptation and survival responses in glioma. Dixit D, Ahmad F, Ghildiyal R, Joshi SD, Sen E. Exp Cell Res. 2016 May 15;344(1):132-142. doi: 10.1016/j.yexcr.2016.03.017. Epub 2016 Mar 18.

Ruchi Ghildiyal 

B.Sc., Delhi University, India

Ph.D., National Brain Research Center, India

Contact:
SRB-4, Lab # 24234
Moffitt Cancer Center
12902 Magnolia Drive
Tampa, Florida 33612

Email:
ruchi.ghildiyal@moffitt.org

Phone:
Lab: 813-745-6025