Welcome to the Karreth Lab

Work in the Karreth lab focuses on understanding the molecular determinants that govern the development of melanoma and ovarian cancer. We combine innovative mouse modeling strategies with various biochemistry and molecular biology techniques to characterize the interaction of non-coding RNAs and oncogenic signaling in tumor initiation, progression, metastasis, and drug resistance. Our goal is to identify cancer cell-specific vulnerabilities that can be harnessed to devise novel therapeutic interventions and precision medicine strategies.

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