2021
Kimmel GJ, Locke FL*, Altrock PM*. The roles of T cell competition and stochastic extinction events in chimeric antigen receptor T cell therapy . Proceedings of the Royal Society B. 2021;288:20210229. PubMed PMID: 33757357 (*co-corresponding authors) Johnson B, Altrock PM*, Kimmel GJ*. Two-dimensional adaptive dynamics of evolutionary public goods games: finite size effects on fixation probability and branching time. Royal Society Open Science. 2021, accepted for publication. (*equal contribution) Miroshnychenko D, Baratchart E, Ferrall-Fairbanks MC, Vander Velde R, Laurie MA, Bui MM, Altrock PM, Basanta D, Marusyk A. Spontaneous Cell Fusions as a Mechanism of Parasexual Recombination in Tumor Cell Populations . Nature Ecology and Evolution. 2021;5:379–391. (pdf ) PubMed PMID: 33462489issue cover:
Damaghi M, West J, Robertson-Tessi M, Xu L, Ferrall-Fairbanks MC, Stewart PA, Persi E, Fridley BL, Altrock PM, Gatenby RA, Sims PA, Anderson ARA, Gillies RJ. The Harsh Microenvironment in Early Breast Cancer Selects for a Warburg Phenotype . PNAS. 2021;118:e2011342118. PubMed PMID: 33452133 Chakiryan NH, Kimmel G, Kim Y, Hajiran A, Aydin A, Zemp L, Katende E, Nguyen J, Lopez-Blanco N, Chahoud J, Spiess P, Fournier M, Dhillon J, Wang L, Moran-Segura C, El-Kenawi A, Mule J, Altrock PM, Manley BJ. Spatial Clustering of CD68+ Tumor Associated Macrophages with Tumor Cells is Associated with Worse Overall Survival in Metastatic Clear Cell Renal Cell Carcinoma . bioRxiv.org. 2021;425197, https://doi.org/10.1101/2021.01.04.425197.
2020
Kimmel GJ, Dane M, Heiser L, Altrock PM, Andor N. Integrating mathematical modeling with high throughput imaging explains how polyploid populations behave in nutrient-sparse environments . Cancer Research. 2020;80:5109. PubMed PMID: 32938640 Enderling H, Altrock PM, Andor N, Basanta D, Brown JS, Gatenby RA, Marusyk A, Rejniak KA, Silva A, Anderson ARA. High school Internship Program in Integrated Mathematical Oncology (HIP IMO)–five-year experience at Moffitt Cancer Center . Bulletin of Mathematical Biology. 2020;82:91. PubMed PMID: 32648152 Ferrall-Fairbanks MC and Altrock PM. Investigating Inter- and Intra-Sample Diversity of Single-Cell RNA Sequencing Datasets. In: Springer Methods in Molecular Biology: Translational Bioinformatics for Therapeutic Development , 2020;2194:177-186. PubMed PMID: 32926367 Kimmel GJ, Locke FL, Altrock PM. Response to CAR T cell therapy can be explained by ecological cell dynamics and stochastic extinction events . bioRxiv.org. 2020;717074, https://doi.org/10.1101/717074 Johnson B, Altrock PM, Kimmel GJ. Branching and extinction in evolutionary public goods games . Preprint: bioRxiv.org. 2020;274399, https://doi.org/10.1101/2020.08.30.274399
2019
Kimmel GJ, Gerlee P, Altrock PM. Time scales and wave formation in non-linear spatial public goods games . PLoS Computational Biology. 2019;15:e1007361. PDF Gerlee P, Altrock PM. Persistence of cooperation in diffusive public goods games . Physical Review E. 2019;99:062412. PubMed PMID: 31330651 Ferrall-Fairbanks MC, Glazar D, Brady R, Kimmel GJ, Zahid MU, Altrock PM*, Enderling H*. Re: Simulation analysis for tumor radiotherapy based on three-component mathematical models . Journal of Applied Clinical Medical Physics. 2019;20:204-205. PubMed PMID: 31145529 (*co-corresponding authors) Ferrall-Fairbanks MC, Ball M, Padron E, Altrock PM. Leveraging single cell RNA sequencing experiments to model intra-tumor heterogeneity . JCO Clinical Cancer Informatics. 2019;2019(3):1-10. PubMed PMID: 30995123 Kimmel GJ, Gerlee P, Brown JS, Altrock PM. Neighborhood size-effects shape growing population dynamics in evolutionary public goods games . Communications Biology. 2019;2(53):1-10. PubMed PMID: 30729189
2018
Altrock PM, Yoon N, Bull JM, Wu H, Ruiz-Ramirez J, Miroshnychenko D, Kimmel GJ, Kim E, Vander Velde RJ, Rejniak K, Manley BJ, Spill F, Marusyk A. The impact of tumor stromal architecture on therapy response and clinical progression . bioRxiv.org. 2018;451047; https://doi.org/10.1101/451047. Altrock PM, Ferlic J, Galla T, Tomasson MH, Michor F. Computational Model of Progression to Multiple Myeloma Identifies Optimum Screening Strategies. .
2017 pre 2017
Werner B, Scott JG, Sottoriva A, Anderson AR, Traulsen A, Altrock PM. The cancer stem cell fraction in hierarchically organized tumors can be estimated using mathematical modeling and patient-specific treatment trajectories . Cancer research. 2016;76(7):1705-13. PubMed PMID: 26833122. Altrock PM, Brendel C, Renella R, Orkin SH, Williams DA, Michor F. Mathematical modeling of erythrocyte chimerism informs genetic intervention strategies for sickle cell disease . American Journal of Hematology. 2016;91(9):931-7. PubMed PMID: 27299299.
Reeves RG, Bryk J, Altrock PM, Denton JA, Reed FA. First steps towards underdominant genetic transformation of insect populations . PloS one. 2014;9(5):e97557. PubMed PMID: 24844466. Marusyk A, Tabassum DP, Altrock PM, Almendro V, Michor F, Polyak K. Non-cell-autonomous driving of tumour growth supports sub-clonal heterogeneity. Nature. 2014;514(7520):54. PubMed PMID: 25079331. Du J, Wu B, Altrock PM, Wang L. Aspiration dynamics of multi-player games in finite populations. Journal of the Royal Society Interface. 2014;11(94):20140077. PubMed PMID: 24598208. Ashcroft P, Altrock PM, Galla T. Fixation in finite populations evolving in fluctuating environments. Journal of The Royal Society Interface. 2014;11(100):20140663. PubMed PMID: 25165604.
